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Real-time, upstream, radiotherapy verification using a Monolithic Active Pixel Sensor System

J J Velthuis, L Beck, Richard Hugtenburg Orcid Logo, J Pritchard, C de Sio

Journal of Physics: Conference Series, Volume: 1662, Start page: 012034

Swansea University Author: Richard Hugtenburg Orcid Logo

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Abstract

Intensity modulated radiotherapy is a widely used technique for accurately targeting cancerous tumours in difficult locations. As treatments are becoming more complex, new methods need to be developed to monitor them. Monolithic active pixel sensors are a viable candidate for providing upstream beam...

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Published in: Journal of Physics: Conference Series
ISSN: 1742-6588 1742-6596
Published: IOP Publishing 2020
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URI: https://cronfa.swan.ac.uk/Record/cronfa55577
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spelling 2025-03-20T15:46:51.0564089 v2 55577 2020-11-02 Real-time, upstream, radiotherapy verification using a Monolithic Active Pixel Sensor System efd2f52ea19cb047e01a01e6fa6fa54c 0000-0003-0352-9607 Richard Hugtenburg Richard Hugtenburg true false 2020-11-02 MEDS Intensity modulated radiotherapy is a widely used technique for accurately targeting cancerous tumours in difficult locations. As treatments are becoming more complex, new methods need to be developed to monitor them. Monolithic active pixel sensors are a viable candidate for providing upstream beam monitoring during treatment. A MAPS based system can be made thin enough to have less than 1% attenuation. We have already demonstrated leaf position resolutions below 130µm at the iso-centre for 5mm wide leaves sampled 34 times per second. We have shown that the signal due to therapeutic photons can be determined and thus the dose in patient. Furthermore, the sensor works well inside an MR-linac, allowing leaf position verification even in that challenging environment. Journal Article Journal of Physics: Conference Series 1662 012034 IOP Publishing 1742-6588 1742-6596 17 10 2020 2020-10-17 10.1088/1742-6596/1662/1/012034 COLLEGE NANME Medical School COLLEGE CODE MEDS Swansea University SU Library paid the OA fee (TA Institutional Deal) Swansea University 2025-03-20T15:46:51.0564089 2020-11-02T12:25:10.0062294 Faculty of Medicine, Health and Life Sciences Swansea University Medical School - Medical Physics J J Velthuis 1 L Beck 2 Richard Hugtenburg 0000-0003-0352-9607 3 J Pritchard 4 C de Sio 5 55577__18789__71cd049584b7469cb90e94550cfc724e.pdf Velthuis_2020_J._Phys.__Conf._Ser._1662_012034.pdf 2020-12-02T13:56:35.1089336 Output 642307 application/pdf Version of Record true This work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. true eng http://creativecommons.org/licenses/by/3.0
title Real-time, upstream, radiotherapy verification using a Monolithic Active Pixel Sensor System
spellingShingle Real-time, upstream, radiotherapy verification using a Monolithic Active Pixel Sensor System
Richard Hugtenburg
title_short Real-time, upstream, radiotherapy verification using a Monolithic Active Pixel Sensor System
title_full Real-time, upstream, radiotherapy verification using a Monolithic Active Pixel Sensor System
title_fullStr Real-time, upstream, radiotherapy verification using a Monolithic Active Pixel Sensor System
title_full_unstemmed Real-time, upstream, radiotherapy verification using a Monolithic Active Pixel Sensor System
title_sort Real-time, upstream, radiotherapy verification using a Monolithic Active Pixel Sensor System
author_id_str_mv efd2f52ea19cb047e01a01e6fa6fa54c
author_id_fullname_str_mv efd2f52ea19cb047e01a01e6fa6fa54c_***_Richard Hugtenburg
author Richard Hugtenburg
author2 J J Velthuis
L Beck
Richard Hugtenburg
J Pritchard
C de Sio
format Journal article
container_title Journal of Physics: Conference Series
container_volume 1662
container_start_page 012034
publishDate 2020
institution Swansea University
issn 1742-6588
1742-6596
doi_str_mv 10.1088/1742-6596/1662/1/012034
publisher IOP Publishing
college_str Faculty of Medicine, Health and Life Sciences
hierarchytype
hierarchy_top_id facultyofmedicinehealthandlifesciences
hierarchy_top_title Faculty of Medicine, Health and Life Sciences
hierarchy_parent_id facultyofmedicinehealthandlifesciences
hierarchy_parent_title Faculty of Medicine, Health and Life Sciences
department_str Swansea University Medical School - Medical Physics{{{_:::_}}}Faculty of Medicine, Health and Life Sciences{{{_:::_}}}Swansea University Medical School - Medical Physics
document_store_str 1
active_str 0
description Intensity modulated radiotherapy is a widely used technique for accurately targeting cancerous tumours in difficult locations. As treatments are becoming more complex, new methods need to be developed to monitor them. Monolithic active pixel sensors are a viable candidate for providing upstream beam monitoring during treatment. A MAPS based system can be made thin enough to have less than 1% attenuation. We have already demonstrated leaf position resolutions below 130µm at the iso-centre for 5mm wide leaves sampled 34 times per second. We have shown that the signal due to therapeutic photons can be determined and thus the dose in patient. Furthermore, the sensor works well inside an MR-linac, allowing leaf position verification even in that challenging environment.
published_date 2020-10-17T04:55:59Z
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score 11.061047